A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells

Articolo

Data di Pubblicazione:

2016

Tipologia CRIS:

01.01 - Articolo in rivista

Keywords:

cardiac arrhythmia; drug screening; hERG; human induced pluripotent stem cells; long-QT syndrome; Cardiovascular Agents; Cells, Cultured; ERG1 Potassium Channel; Humans; Induced Pluripotent Stem Cells; Long QT Syndrome; Myocytes, Cardiac

Elenco autori:

Sala, L.; Yu, Z.; Ward-van Oostwaard, D.; Van Veldhoven, J. P. D.; Moretti, A.; Laugwitz, K. -L.; Mummery, C. L.; Ijzerman, A. P.; Bellin, M.

Autori di Ateneo:

BELLIN MILENA

Link alla scheda completa:

https://www.research.unipd.it/handle/11577/3321894

Pubblicato in:

EMBO MOLECULAR MEDICINE

Journal

Dati Generali

URL

http://embomolmed.embopress.org/

A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells

Sala, L.; Yu, Z.; Ward-van Oostwaard, D.; Van Veldhoven, J. P. D.; Moretti, A.; Laugwitz, K. -L.; Mummery, C. L.; Ijzerman, A. P.; Bellin, M.

EMBO MOLECULAR MEDICINE

Dati Generali

URL